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NION FORTE

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NION FORTE promotes growth of cartilage tissue


The effectiveness of NION FORTE has been scientifically proven in numerous studies. According to published research, orally  administered NION FORTE is absorbed intestinally and accumulates in cartilage. The ingestion of NION FORTE stimulates a statistically significant increase of cartilage tissue metabolism.


 Benefits:


1)  Activates cartilage growth up to 70%


2)  Stimulates cells that help reduce joint discomfort


3)  Smooth the joints of fingers, shoulders, legs, knees, spine and it will help for ease of movement of the body


CLINICAL STUDIES

MAIN ACTIVE FORMULA - FORTIGEL

Penn State study confirms improvement of mobility with FORTIGEL®


At Penn State University (USA, 2008), 147 athletes were recruited who experienced activity-related joint pain. Those athletes (mean age 20.1 years) were subdivided into one group taking FORTIGEL® as a nutritional supplement and a control group taking a placebo for 24 weeks. The severity of symptoms was rated both by the treating physician and by the study participants with a visual analogue scale.


In this prospective, randomized, double-blind, placebo-controlled study, it was interesting to observe a statistically significant difference of pain perception between treatment and control groups. When utilizing alternative therapies such as hydrotherapy, massage and ice and heat packs, there was a clear-cut difference between the treatment and the placebo group in favor of the FORTIGEL® group. This was the first trial to show improvement of joint pain in healthy athletes treated with FORTIGEL®.


In summary, the studies confirm that the intake of FORTIGEL® results in improvement of mobility in healthy individuals.



McAlindon proves long term effect of FORTIGEL®


In a study published in March 2011 by McAlindon and colleagues, the long term effect of FORTIGEL® treatment on the composition of hyaline cartilage in individuals with early knee osteoarthritis was investigated. This prospective, randomized, double-blind, placebo-controlled pilot study was performed at the Tufts Medical Center in cooperation with Harvard University.


A specific type of magnetic resonance imaging (dGEMRIC) was utilized in order to visualize structural changes in cartilage tissue of the respective study participants. Overall, 30 subjects were randomized into one group receiving 10 g FORTIGEL® a day for 48 weeks and a control group receiving a placebo. 


Three MRI scans of the knee were performed on each subject, one at baseline, one at 24 weeks with the final scan at 48 weeks.


The analysis of the cartilage scans revealed a statistically significant increase in proteoglycan density in the medial and lateral tibial regions of the FORTIGEL® treated subjects compared to the placebo group. Results indicate that oral supplementation of FORTIGEL® has a direct impact on human cartilage tissue. 


This confirms previous experimental data and clearly demonstrates that specific orally administered collagen peptides can have an influence on cartilage tissue regeneration. It can be assumed that this observed effect is not limited to pathophysiological conditions, as indicated by additional clinical studies.

• Stimulating bone matrix formation



University of Freiburg, Germany confirms mobility improvement
in young adults


Intention of the mono centric, placebo-controlled, randomized, double-blind, observational trial on 160 subjects at the Institute for Sports and Sports Science, University of Freiburg, Germany was to investigate the effect of orally administered Bioactive Collagen Peptides (BCP®) on young adults suffering from diagnosed activity-related knee joint pain. In the study a daily dosage of 5 g FORTIGEL® or a placebo was orally administered for 12 duration of weeks. After 3, 6, and 12 weeks changes in pain, stiffness and physical function were evaluated in the FORTIGEL® group using the Western Ontario and McMaster Universities Index score (WOMAC)4.


The results of the study clearly demonstrate the efficacy of a daily intake of 5 g FORTIGEL® in the treatment of gon- and coxarthritis. After only 3 weeks of oral administration of the product a statistically significant improvement in pain, stiffness and physical function could be observed. Moreover, this positive effect of FORTIGEL® persisted and was even more pronounced after 6 and 12 weeks of treatment.


At the same time secondary treatments such as massage and physiotherapy have been substantially reduced. The increased mobility was accompanied by a statistically significantly reduction in stiffness and a clear pain relief. In more than 40 % of all patients a complete pain reduction was achieved and in 70 % a positive effect of the therapy could be demonstrated. Thus FORTIGEL® is an effective therapeutic approach for those suffering from knee- and hip conditions.



FORTIGEL® preserves quality of life


Based on the presented data it can be concluded that the oral administration of FORTIGEL® has a beneficial effect on cartilage tissue. Consequently, supplementation of FORTIGEL® peptides can contribute to the maintenance of joint health and could help to preserve mobility and quality of life.


Technological properties

FORTIGEL® is a natural protein of neutral odor and taste that can be easily implemented into many applications. It provides excellent solubility and delivers clear solutions without interacting with other ingredients.


Make innovative product ideas a reality!

FORTIGEL® can enhance the most diverse of foodstuffs, including dairy products, functional food, dietary supplements and drinks.


FORTIGEL® promotes

  •  Clean label (no E numbers)
  •  Highly digestible Food
  •  Non-allergenic Food
  •  Scientific evidence

Learn More

Specific collagen peptides benefit the biosynthesis of matrix molecules of tendons and ligaments

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